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From SAGES Surgical Wiki
Welcome to The SAGES Surgical WIKI
Contents |
About SAGES
Categories
- Bariatric Surgery
- Chest
- Colon,Rectum, and Anus
- Emerging Technologies
- Endocrine
- Esophagus
- Flexible Endoscopy
- Gynecology
- Hepatobiliary
- Hernia
- Minimally Invasive Surgery
- Pediatric Surgery
- Perioperative Management
- Small Intestine
- Spleen
- Stomach and Foregut
- Transplantation
- Trauma and Critical Care
- Urology
Resources
WIKI Resources
SAGES Online Resources
SAGES represents a worldwide community of surgeons that can bring minimal access surgery, endoscopy and emerging techniques to patients in every country. We represent over 6,000 surgeons and allied health professionals.
The mission of the society is:
- To provide education and training for gastrointestinal and/or abdominal surgeons and surgeons-in-training.
- To measure, on an ongoing basis, the quality and effectiveness of our educational programs and to modify them based on these measures.
- To identify and evaluate current and emerging minimal access and non invasive technologies and techniques in gastrointestinal endoscopy and endoscopic surgery.
- To serve as a forum for ideas and the exchange of information in current and emerging minimal access technology and techniques.
- To foster, support, and encourage clinical and basic science research.
- To provide guidelines for training, standards of practice and granting of privileges which promote patient safety and the best clinical outcomes.
- To help assure that patients are able to obtain the most effective diagnosis and treatment from qualified surgeons.
- To develop, maintain and provide leadership to achieve the above goals.SAGES Mission Statement
- To maintain an atmosphere which promotes diversity and collegiality among members.
- To define and provide tools and guidelines for measurement in assessing surgical competence.
Gastrointestinal Stromal Tumor (GIST)
Overview:
Gastrointestinal stromal tumor (GISTs) are the most common mesenchymal tumor of the GI tract and originate from the intestinal pacemaker cells, the interstitial cells of Cajal. It is distinguished from other mesenchymal tumors (e.g. leiomyoma, schwannoma) through immunohistochemistry identifying markers of GIST, which are equally expressed in interstitial cells of Cajal: CD117 (KIT) - gene product of stem cell factor receptor proto-oncogene c-kit; CD34 - hematopoietic progenitor cell antigen; PDGF receptor alpha (PDGFRA) - alternative and mutually exclusive oncogenic mechanisms to c-kit pathway.
